Magnetic Activated Cell Sorting (MACS) is an advanced sperm selection technique used in fertility treatments like IVF and ICSI. It helps embryologists separate healthy, functional sperm from those that may carry DNA damage or markers of apoptosis (cell death). This increases the chances of successful fertilisation, healthy embryo development, and pregnancy.
India has become a hub for fertility technologies like MACS, thanks to world-class IVF labs, skilled embryologists, and significantly lower costs compared to the West. VivaVel Health connects international patients with top fertility centres in India, offering comprehensive medical tourism support.
Infertility
Doctors may recommend MACS when there is a higher risk of sperm abnormalities, including:
Repeated IVF or ICSI failures
High sperm DNA fragmentation
Unexplained infertility
History of recurrent miscarriages
Advanced male age (when sperm quality declines)
Poor semen analysis results (low motility, morphology issues)
Couples should see a fertility specialist and ask about MACS if:
They have attempted IVF/ICSI multiple times without success.
They have undergone two or more miscarriages
The male partner has poor semen quality or abnormal test results.
Standard sperm washing techniques did not improve outcomes.
Before MACS, couples typically undergo:
Semen analysis (count, motility, morphology)
Sperm DNA fragmentation test
Hormonal evaluation (testosterone, FSH, LH in men)
General fertility workup (AMH, ultrasound for women)
Do's:
Follow a healthy lifestyle to improve sperm health (such as eating well, avoiding smoking, and limiting alcohol).
Finish all the tests recommended by the fertility specialist.
Remain engaged in the IVF/ICSI treatment process
Don'ts:
Avoid delaying treatment if recurrent IVF failures happen.
Don't rely on MACS alone – it is only one part of fertility treatment
Recovery & Outlook
No physical recovery is required since MACS is performed outside the body.
Studies have shown higher fertilisation rates, embryo quality, and pregnancy outcomes when MACS is used in couples with sperm quality issues.
It reduces the risk of miscarriage due to abnormal sperm DNA.
Success Rate Improvement with MACS:
Pregnancy rates may improve by 10–15% compared to conventional ICSI in select patients.
Best outcomes seen in couples with recurrent IVF failures or high sperm DNA fragmentation.
Why Choose VivaVel Health for MACS in India?
At VivaVel Health, we help couples access India's top fertility centres with advanced sperm selection technologies, such as MACS.
Top IVF Labs in India: Equipped with MACS & modern embryology tools
Expert Embryologists: Skilled in advanced sperm selection techniques
Affordable Packages: Significant savings compared to the West
End-to-End Assistance: Visa, travel, stay, translators, aftercare
Compassionate Guidance: Supporting couples through emotional challenges of infertility
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Saba holds a Master’s degree in Pharmacy from Jamia Hamdard University, New Delhi and possesses a deep understanding of medical subjects. She is an experienced teacher and is passionate about health education. She has a remarkable talent for transforming complex medical concepts into engaging, accurate, and impactful content to inspire healthier living. With a deep scientific understanding and thorough research, Saba consistently supports her writings with the latest publications, ensuring accuracy and relevance.
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Oruge is committed to promoting health awareness through clear, research-based communication. With a background in microbiology and public health, she combines scientific accuracy with an engaging writing style to simplify complex medical topics. At VivaVel Health, she contributes insightful reviews, articles, and blogs that empower readers to make informed decisions for healthier living.
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